Researchers from Boston University School of Medicine (BUSM) have determined the optimal dose-management strategy to derive maximal benefit from warfarin therapy and improve patient outcomes. Results of the study appear online in the December 2008 issue of the Journal of Thrombosis and Haemostasis.

Researchers have made several, subtle changes in the structure of a key protein, dramatically increasing its ability to drive blood clotting, according to a study published in a December edition of the Journal of Thrombosis and Haemostasis.

Deep venous thrombosis (DVT), the formation of blood clots in the lower limbs, is the third-most common vascular disease in North America after heart attack and stroke, and is a frequent complication in hospitalized patients.

Being male increases your risk of diseases caused by the inappropriate formation of a blood clot (a process known as thrombosis), such as heart attack and stroke, but the reasons for this are not completely understood.

New evidence-based guidelines address the prevention and management of thrombosis in key patient populations and reinforce recommendations related to the routine use of preventive therapies.

Hip and knee replacement surgery patients – who are often elderly – are at increased risk of developing potentially life-threatening thrombosis, or blood clots.

Researchers from Weill Cornell Medical College may have discovered the precise role of a gene in one of the world's most common blood disorders, beta-thalassemia, commonly known as Cooley's anemia. Along with sickle-cell anemia, Cooley's anemia is the most commonly inherited disease in the world, affecting many people of Mediterranean descent, and 20 out of every 100,000 African-Americans.

Coalition to Prevent Deep-Vein Thrombosis (DVT) partners with Parsons The New School for Design to create new awareness icon featuring celebrities such as Broadcaster Bonnie Bernstein, NBC's TODAY Show Ann Curry and Natalie Morales, among others.

"The blood froze in my veins" or "My blood curdled" – these common figures of speech can be taken literally, according to the latest studies. Indeed, more literally than some of us would like. For it turns out that intense fear and panic attacks can really make our blood clot and increase the risk of thrombosis or heart attack.

Among the 118 patients with portal vein thrombosis, noncirrhotic and nontumoral extrahepatic portal vein obstruction are young and present with well tolerated bleed. Cirrhosis and tumor related portal vein thrombosis patients are older and have grim prognoses. Hypercoagulable state as a cause of portal vein thrombosis is less common.

In a paper published this week in the open-access journal PLoS Medicine Frits Rosendaal and colleagues from Leiden University Medical Center, Academic Medical Center Amsterdam and Nestlй Medical Services, provide the first absolute estimate of risk of venous thrombosis after air travel.

In women, hormone therapy is a risk factor for venous thrombosis, a blood clot forming deep inside the vein. Despite the fact that the disorder is rare, it increases exponentially during menopause and can be deadly. The hormone trials conducted thus far, focusing on proteins in blood coagulation, have not yet led to a risk profile, thereby precluding identification of women at risk.