type 2 diabetes

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Canadian scientist mines drugs database for new diabetes treatment

A Canadian scientist, now based in the UK and funded by the UK Biotechnology and Biological Sciences Research Council, has harnessed a new drug discovery tool to identify a new player in the body's insulin secretion process. This finding could spark a completely new class of drugs to treat type 2 diabetes.

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Fetal heath affected by mother's diet

In the United States, there has been a recent dramatic rise in the number of children classified as obese and diagnosed with obesity-related diseases, such as type 2 diabetes and nonalcoholic fatty liver disease (NAFLD).

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Advance toward first saliva test for Type 2 diabetes

Scientists in Oregon and India are reporting an advance toward developing the first saliva test to diagnose and monitor effectiveness of treatment for Type 2 diabetes.

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Same mortality risks in men with type 2 diabetes and cardiovascular disease

Men with type 2 diabetes and men with previous heart attack or stroke had a 3 to 4 fold risk of cardiovascular death compared to men without either disease in the years following the first acute event.

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Siblings of diabetic children likely to have abnormal blood sugar levels

Overweight siblings of children with type 2 diabetes are four times more likely to have abnormal glucose levels compared to other overweight children. Because abnormal glucose levels may indicate risk for diabetes or diabetes itself, these children could benefit from screening tests and diabetes prevention education.

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Popular class of diabetes drugs doubles risk of fractures in women

New findings out of Wake Forest University School of Medicine and the University of East Anglia show that long-term use of a popular class of oral diabetic drugs doubles the risk of fractures in women with type 2 diabetes.

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Gene variation in diabeteics associated with risk of coronary artery disease

Patients with type 2 diabetes who have poor glycemic control and a certain genetic variation have an increased risk of coronary artery disease, according to a study in the November 26 issue of JAMA.

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Potassium loss from blood pressure drugs may explain higher risk of adult diabetes

Johns Hopkins researchers have discovered that a drop in blood potassium levels caused by diuretics commonly prescribed for high blood pressure could be the reason why people on those drugs are at risk for developing type 2 diabetes.

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Low-dose aspirin does not reduce risk of cerebrovascular events in diabetics

Low-dose aspirin as primary prevention did not appear to significantly reduce the risk of a combined end point of coronary, cerebrovascular and peripheral vascular events in patients with type 2 diabetes, according to a new study in JAMA. However, aspirin did significantly reduce the combination of fatal coronary and fatal cerebrovascular events.

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Apelin hormone injections powerfully lower blood sugar

By injecting a hormone produced by fat and other tissues into mice, researchers report in the November Cell Metabolism that they significantly lowered blood sugar levels in normal and obese mice. The findings suggest that the hormone known as apelin might be a promising target for managing insulin resistance and type 2 diabetes.

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Tweens and teens double use of diabetes drugs

America's tweens and teens more than doubled their use of type 2 diabetes medications between 2002 and 2005, with girls between 10 and 14 years of age showing a 166 percent increase. One likely cause: Obesity, which is closely associated with type 2 diabetes.

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Moderate use averts failure of type 2 diabetes drugs

Drugs widely used to treat type 2 diabetes may be more likely to keep working if they are used in moderation, researchers at Washington University School of Medicine in St. Louis have found in a study using an animal model.

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