JAMA's editor, Catherine D. DeAngelis, said her journal had been duped by a ghostwritten manuscript in 2002 that compared Vioxx with two competitors' drugs for knee pain, and she acknowledged that editors bore some responsibility, writes Philly Inquirer's Kari Stark.

While you thought that those Vioxx studies in medical journals were independent, hands-off affairs that may not have been necessarily true. An examination of medical journal articles about Vioxx and court documents from Vioxx lawsuits found that Merck employees or ghostwriters were frequently involved in various articles, but the primary authors were often academics who actually had little to do with the studies or didn’t always disclose financial ties to Merck.

Merck Agreement Provides for $4.85 Billion Vioxx Settlement Payment.

Vioxx and related pain medications were taken off the market in 2004 because they caused dangerous heart problems in some people. A group of scientists, led by Timothy Hla at the University of Connecticut, may now have figured out how these drugs trigger these life-threatening side-effects.