X chromosomes

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Variants in gene on X chromosome associated with susceptibility to Alzheimer's

Researchers at Mayo Clinic have discovered the first gender-linked susceptibility gene for late-onset Alzheimer's disease.

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Switch that turns on X chromosome matchmaking

A research group lead by scientists at the University of Warwick has discovered the trigger that pulls together X chromosomes in female cells at a crucial stage of embryo development. Their discovery could also provide new insights into how other similar chromosomes spontaneously recognize each other and are bound together at key parts of analogous cell processes.

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Bird-like sex-determination system of mammalian ancestors

Therian mammals possess an XY sex-determination system, where females have a pair of X chromosomes, and males harbor one X and one Y chromosome. However, the sex-determination system of platypus stands in stark contrast: the female has five different pairs of X chromosomes, while males have five X chromosomes and five Y chromosomes.

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How do you know whether you are male or female?

New research published online this week in the open-access journal PLoS Biology investigates this basic and much-studied question in the fruit fly, and comes to a surprising new conclusion.

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Female Chromosome Confirmed Prime Driver of Speciation

Researchers at the University of Rochester believe they have just confirmed a controversial theory of evolution. The X chromosome is a strikingly powerful force in the origin of new species.

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Physicist cracks women's random but lucky choice of X chromosome

A University of Warwick physicist has uncovered how female cells are able to choose randomly between their two X chromosomes and why that choice is always lucky.

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New gene associated with Wilms tumor

Mutations to gene on X chromosome found in 30 percent of pediatric kidney cancer cases

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