neuronal cells

REST and miRNAs Provide Double Negative Feedback

harminka — Wed, 31 Dec 2008 07:18:01 -0600

RE1-silencing transcription factor (REST) inhibits expression of neuronal genes in non-neural cells. Huntingtin sequesters REST in the cytoplasm of neurons, precluding transcriptional repression and allowing neuronal specification.

Neuronal Activation by Astrocytic Calcium

harminka — Wed, 25 Jun 2008 04:08:24 -0500

Increases in intracellular calcium cause astrocytes to release glutamate, but evidence that this glutamate produces currents in neurons has been contradictory.

Neuronal regulators offer potential targets for cancer

harminka — Thu, 20 Mar 2008 03:23:12 -0500

Being too brainy can be a bad thing in a junior high cafeteria, where the social hierarchy favors other traits. "Braininess" also causes problems for cells. When a breast cell begins making the proteins normally produced in neurons, for example, it can acquire cancerous properties.

Targeting nerve growth factor may cure liver cancer

harminka — Fri, 07 Sep 2007 13:52:29 -0500

Nerve growth factor (NGF), as the name says, is an essential peptide factor for the growth and differentiation of neuronal cells. Therefore we can imagine that this growth factor is important for the nervous system including brain.

Iron nanoparticles exhibit toxic effects on neuronal cells

harminka — Thu, 29 Mar 2007 05:54:51 -0500

Researchers at UC San Diego have discovered that iron-containing nanoparticles being tested for use in several biomedical applications can be toxic to nerve cells and interfere with the formation of their signal-transmitting extensions.

Proteasome activator enhances survival of neuronal model cells

harminka — Wed, 28 Feb 2007 04:41:12 -0600