insulin resistance

Inheritance of hormonal disorder marked by excessive insulin in daughters

harminka — Tue, 29 Jul 2008 14:21:15 -0500

Elevated levels of insulin could be an early sign that girls whose mothers suffer from polycystic ovary syndrome -- or PCOS -- may also be susceptible to the disease, according to gynecologists who have found evidence of insulin resistance in young children.

Lifestyle can alter gene activity, lead to insulin resistance

harminka — Thu, 19 Jun 2008 01:18:39 -0500

A Finnish study of identical twins has found that physical inactivity and acquired obesity can impair expression of the genes which help the cells produce energy. The findings suggest that lifestyle, more than heredity, contributes to insulin resistance in people who are obese.

Is There A Link Between Frailty And Insuline Resistance

admin_huliq — Sun, 30 Mar 2008 13:26:27 -0500

Two of the great scourges of old age are insulin resistance (often leading to late-onset diabetes) and frailty (a suite of symptoms that may have their roots in runaway inflammatory signaling). A review by Paolisso and Abbatecola investigates the possible connections between the two:

Novel link between excessive nutrient levels and insulin resistance

harminka — Fri, 22 Feb 2008 13:58:01 -0600

For quite some time now, scientists suspected the so-called hexosamine pathway — a small side business of the main sugar processing enterprise inside a cell — to be involved in the development of insulin resistance. But they could never quite put their finger on the underlying mechanism.

How does insulin influence resistin?

harminka — Wed, 16 Jan 2008 09:07:28 -0600

Obesity is a worldwide health problem directly linked to several diseases such as hypertension and type 2 diabetes. Resistin is a cysteine-rich hormone mainly secreted by adipose tissues and may form a biochemical link between obesity and type 2 diabetes.

Morbidly obese mice gain protection against diabetes

harminka — Fri, 24 Aug 2007 13:08:15 -0500

The “world’s fattest mice” can overeat without developing insulin resistance or diabetes thanks to a glut of a key hormone, a dichotomy that helps explain why not all obese people are diabetic, a UT Southwestern Medical Center researcher has found.

Fat on chest increases risk of insulin resistance

harminka — Mon, 20 Aug 2007 03:46:32 -0500

Upper trunk fat – deposits of fat on the chest and back –– is associated with an increased risk of insulin resistance, a condition that is a precursor of type 2 diabetes, according to a study led by researchers at the San Francisco VA Medical Center (SFVAMC).

New clue into how diet, exercise enhance longevity

harminka — Fri, 20 Jul 2007 04:00:34 -0500

The traditional prescriptions for a healthy life—sensible diet, exercise and weight control—extend life by reducing signaling through a specific pathway in the brain, according to Howard Hughes Medical Institute researchers who discovered the connection while studying long-lived mice.

New blood test to offer warning of deep belly fat

harminka — Tue, 10 Jul 2007 11:28:41 -0500

Measuring levels of a chemical found in blood offers the best indicator yet of the amount of fat surrounding abdominal organs, according to a new study of lean and obese individuals reported in the July issue of Cell Metabolism, a publication of Cell Press.

ContraveHas Positive Effect on Visceral Fat and Insulin Resistance

Anastvatz — Sat, 23 Jun 2007 15:23:10 -0500

Orexigen(TM) Therapeutics Reports that data is to be presented on June 23rd at the American Diabetes Association 67th Scientific Sessions in Chicago.

Resistin action in brain linked to liver insulin resistance

harminka — Mon, 28 May 2007 12:56:05 -0500

Resistin is a small protein secreted by the immune cells monocytes and macrophages, and has been linked to insulin resistance, atherosclerosis, and inflammation. Recently, studies in mice have shown that resistin is present in the mouse hypothalamus and that it is capable of activating specific neurons.

Scavenger cells may have role blocking obesity

harminka — Mon, 21 May 2007 12:44:33 -0500

Macrophages - the scavenger cells of the body's immune system - are known as troublemakers for the role they play in obesity, but Stanford University School of Medicine researchers have found that the cells can also be saviors when it comes to metabolism.