childhood leukemia

New Drug For Childhood Leukemia Discovered

harminka — Tue, 28 Jul 2009 14:08:09 -0500

Each year, approximately 4,500 children in America are diagnosed with leukemia, according to the Leukemia and Lymphoma Society. A potentially deadly cancer of the blood, it is the most common cancer in children.

How Tumor Cells invade Brain in Childhood Cancer

harminka — Wed, 17 Jun 2009 13:29:46 -0500

Despite great strides in treating childhood leukemia, a form of the disease called T-cell acute lymphoblastic leukemia (T-ALL) poses special challenges because of the high risk of leukemic cells invading the brain and spinal cord of children who relapse.

Adult survivors of childhood cancer have lower bone mineral density

harminka — Wed, 03 Dec 2008 15:01:52 -0600

Men who survived childhood leukemia treatment into adulthood were more likely to have low bone mineral density than other adults their age, putting them at risk of osteoporosis and bone fractures, according to a new study.

Study reveals basis of anticancer drug resistance in childhood leukemia

harminka — Wed, 16 Apr 2008 05:55:47 -0500

The first analysis of the genetic determinants of resistance to the anti-cancer drug methotrexate in childhood acute lymphoblastic leukemia (ALL) could offer a pathway to predicting such resistance and treatments to overcome it, according to a St. Jude Children’s Research Hospital study.

Genetic basis of resistance to chemotherapy in children with acute leukemia

harminka — Tue, 15 Apr 2008 13:14:11 -0500

In a new study published in PLoS Medicine, William Evans of St Jude Children’s Research Hospital, Memphis, and colleagues provide new insight into resistance to the widely-used cancer drug methotrexate (MTX) in patients with acute lymphoblastic leukaemia (ALL), the most common cancer in children.

Childhood leukemia survivors struggle with long-term comorbidities

harminka — Tue, 01 Apr 2008 12:26:02 -0500

Survival rates of childhood cancers, especially leukemia, have improved greatly in the past three decades, but survivors of this disease still seem to face many health and lifestyle challenges as young adults.

Molecular science could further improve leukemia survival, say St. Jude researchers

harminka — Fri, 21 Mar 2008 14:41:05 -0500

The dramatic increase that has occurred in the cure rate for children with acute lymphoblastic leukemia (ALL) will be difficult to replicate in older patients without considerable additional research, according to an article by St. Jude Children’s Research Hospital authors that appears in the March 22 issue of the Lancet.

Cancer pill Gleevec delivers more good news to patients

harminka — Mon, 10 Dec 2007 00:01:00 -0600

Gleevec, the targeted cancer pill that has saved more than 100,000 lives, now is saving more children with a dire leukemia, as well as preventing disease progression with long term use in adults with chronic myeloid leukemia.

Unique role for blood formation gene identified

harminka — Wed, 12 Sep 2007 12:25:38 -0500

All blood cell production in adults depends on the steady work of a vital gene that if lost results in early bone marrow failure, Dartmouth Medical School cancer geneticists have found. Their research reveals an unexpected role for the gene in sustaining the adult blood-forming system, and opens novel strategies for targeting the gene, which is often involved in a type of childhood leukemia.

Adult survivors of childhood leukemia worsening high risk for obesity

harminka — Mon, 23 Jul 2007 12:50:54 -0500

Inherited genes linked to toxicity of leukemia therapy

harminka — Sat, 12 May 2007 08:32:47 -0500

St. Jude researchers discover that variations in genes that affect the behavior of leukemia chemotherapy drugs in the body are linked to drug toxicity, a finding that will likely help clinicians predict how patients will respond to specific agents

Tree Rings show elevated tungsten coincides with Nevada leukemia cluster

harminka — Tue, 01 May 2007 08:41:28 -0500

Tungsten began increasing in trees in Fallon, Nev. several years before the town's rise in childhood leukemia cases, according to a new research report.