chemotherapy drugs

New way to targeted cancer treatments

harminka — Thu, 24 Sep 2009 12:45:08 -0500

UC Irvine researchers have created a new approach that vastly improves the targeting of chemotherapeutic drugs to specific cells and organs.

How cancer cells survive chemotherapy drug

harminka — Wed, 28 Jan 2009 11:56:54 -0600

What separates the few cancer cells that survive chemotherapy – leaving the door open to recurrence – from those that don’t? Weizmann Institute scientists developed an original method for imaging and analyzing many thousands of living cells to reveal exactly how a chemotherapy drug affects each one.

Simple ways to judge efficacy of 5-fluorouracil in colonic neoplasm?

harminka — Sat, 23 Feb 2008 11:59:12 -0600

5-fluorouracil (5-FU) is a common chemotherapeutical drug. It exerts its antitumor effect through competitive thymidylate synthase (TS) inhibition. Thymidylate synthase (TS) catalyses deoxyuridine-5ЎЇ-monophosphate (dUMP) to 2ЎЇ-deoxythymydine-5ЎЇ-monophosphate (dTMP).

Drug helps brain tumor patients live longer

harminka — Tue, 29 Jan 2008 09:47:10 -0600

People who receive high doses of the chemotherapy drug methotrexate to treat a certain type of brain tumor appear to live longer than people receiving other treatments, according to research published in the January 29, 2008, issue of Neurology®, the medical journal of the American Academy of Neurology.

Anthracyclines improve survival in HER2-positive breast cancer patients

harminka — Wed, 26 Dec 2007 07:10:36 -0600

Treatment with the class of chemotherapy drugs called anthracyclines improves survival in women with HER2-positive breast cancer who have previously had surgery, but it may not offer any benefit for women with HER2-negative tumors, according to a study published online December 25 in the Journal of the National Cancer Institute.

Genomic profiling of lung tumors helps doctors choose most effective treatment

harminka — Sat, 29 Sep 2007 02:52:36 -0500

Determining the genetic profile of a particular lung tumor can help clinicians make the crucial decision about which chemotherapy treatment to try first.

Molecular pathway may predict chemotherapy effectiveness

Dinka — Sat, 01 Sep 2007 09:21:44 -0500

A common molecular pathway could help physicians predict which lung cancer patients will benefit from chemotherapy drugs, according to new research from a multidisciplinary team at the University of Cincinnati (UC).

Temporary improvement of tumor blood flow can improve chemotherapy

harminka — Thu, 12 Jul 2007 06:39:45 -0500

A treatment for neuroblastoma that lands a one-two punch works best when the second punch is timed to take maximum advantage of the first one, according to results of studies at St. Jude Children’s Research Hospital. Neuroblastoma is a pediatric solid tumor that arises from cells in the peripheral nervous system.

Nanoparticles carry chemotherapy drug deeper into tumors

harminka — Wed, 27 Jun 2007 10:27:09 -0500

A new drug delivery method using nano-sized molecules to carry the chemotherapy drug doxorubicin to tumors improves the effectiveness of the drug in mice and increases their survival time, according to a study published online June 26 in the Journal of the National Cancer Institute.

Massive gene screening points for effective chemotherapy

harminka — Thu, 12 Apr 2007 11:29:30 -0500

Using a technology that can quickly screen all 20,000-plus human genes for biological activity, scientists have isolated 87 genes that seem to affect how sensitive human cancer cells are to certain chemotherapy drugs.

Massive gene screening points way to more effective chemotherapy

harminka — Wed, 11 Apr 2007 13:15:03 -0500

One-two punch result of chemotherapy drug

harminka — Wed, 21 Feb 2007 02:14:32 -0600