rheumatoid arthritis treatment

Molecule Triggering Inflammation in Rheumatoid Arthritis

harminka — Sun, 28 Jun 2009 14:04:52 -0500

A signal molecule made by the human body that triggers the immune system into action may be important in rheumatoid arthritis, according to new research published today in Nature Medicine. The authors of the study, from Imperial College London, say that if scientists could block this signal, it may be possible to develop more effective arthritis treatments.

New Drug Promise For Rheumatoid Arthritis Treatment

harminka — Sat, 27 Jun 2009 11:52:51 -0500

A clinical trial of masitinib, a drug in development for the treatment of rheumatoid arthritis, has shown it to be well tolerated and effective. Researchers writing in BioMed Central's open access journal Arthritis Research and Therapy have shown that treatment with masitinib significantly reduced the severity of active rheumatoid arthritis.

Anakinra for rheumatoid arthritis

harminka — Wed, 21 Jan 2009 03:25:04 -0600

New research supports a modest beneficial effect of anakinra for rheumatoid arthritis patients, but warns against potential risks for serious infections and its use with other biologic medications.

New Drugs Target Rheumatoid Arthritis Pathways

harminka — Wed, 14 Jan 2009 04:01:15 -0600

Methotrexate (MTX), a folate antagonist that blocks folic acid activity, is the most widely used disease-modifying antirheumatic drug (DMARD) for rheumatoid arthritis. It enters the cell via several pathways, one of which involves folate receptor β (FRβ), which is highly specific for cells present in the joints of patients with rheumatoid arthritis (RA).

Rheumatoid arthritis drug variability suggests alternative dosing

harminka — Wed, 05 Nov 2008 07:47:45 -0600

Methotrexate (MTX) is commonly used to treat rheumatoid arthritis (RA) and is suggested as the "anchor" drug in treating the disease. Despite its widespread use, the understanding of its mechanism of action and pharmacokinetics is limited.

Medicaid policies vary for arthritis drugs

harminka — Wed, 05 Nov 2008 07:37:58 -0600

Patients with inflammatory diseases such as rheumatoid arthritis now have many more treatment options than in the past, including biologic disease-modifying antirheumatic drugs (DMARDs).

New guidelines for treating rheumatoid arthritis

harminka — Thu, 24 Jul 2008 02:09:17 -0500

Proven combinations of medicines and the introduction of new anti-arthritis drugs have significantly improved the treatment of rheumatoid arthritis (RA), according to guidelines issued by the American College of Rheumatology and co-authored by physicians at the University of Alabama at Birmingham (UAB).

Novel DNA microarray chip predicts functional impairment in rheumatoid arthritis

harminka — Fri, 13 Jun 2008 13:10:20 -0500

A new DNA microarray chip can predict severe disability and remission in patients with rheumatoid arthritis (RA), as presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France.

New insight into RA patient priorities, motivators for clinical trial involvement

harminka — Fri, 13 Jun 2008 13:07:52 -0500

Two new initiatives designed to improve the management of rheumatoid arthritis through patient participation were presented today at EULAR 2008, the Annual Congress of the European League Against Rheumatism in Paris, France.

Higher prevalence of periodontal disease in rheumatoid arthritis patients

harminka — Wed, 11 Jun 2008 04:23:50 -0500

Over 1.3 million Americans suffer from rheumatoid arthritis (RA), a chronic, inflammatory disease of the joints. RA is a disabling condition, and can lead to long-term joint damage resulting in persistent pain and loss of function in affected areas.

Recommendations for Rheumatoid Arthritis Therapy

harminka — Wed, 04 Jun 2008 08:11:31 -0500

To manage the painful and incapacitating symptoms of rheumatoid arthritis (RA), a chronic, inflammatory joint disease, the majority of patients rely on disease-modifying antirheumatic drugs (DMARDs). In addition to trusted nonbiologic DMARDs, a number of biologic agents now promise to improve treatment for RA.

Decline in Work Disability Due to Rheumatoid Arthritis

harminka — Tue, 15 Apr 2008 11:41:36 -0500

Rheumatoid arthritis (RA) is a chronic inflammatory disease affecting the joints and, in severe cases, vital organs. Marked by pain, fatigue, and loss of dexterity and mobility, RA has been strongly associated with work disability in the US. In previous studies of patients with advanced RA, 10 years in duration, the prevalence of work disability has been estimated at as high as 50 percent.