Lou Gehrig's disease

Gene find sheds light on motor neuron diseases like ALS

harminka — Wed, 22 Oct 2008 13:03:36 -0500

Scientists have identified a gene in mice that plays a central role in the proper development of one of the nerve cells that goes bad in amyotrophic lateral sclerosis, or Lou Gehrig's disease, and some other diseases that affect our motor neurons.

Protein plays Jekyll and Hyde role in Lou Gehrig's disease

harminka — Tue, 29 Jul 2008 08:45:09 -0500

Amyotrophic lateral sclerosis (ALS), more commonly known as Lou Gehrig's disease, is a fatal neurodegenerative disease caused by the death of motor neurons in the brain and spinal cord that control muscle movements from walking and swallowing to breathing.

Lou Gehrig's protein found throughout brain

harminka — Tue, 17 Jun 2008 08:34:15 -0500

Two years ago researchers at the University of Pennsylvania School of Medicine discovered that misfolded proteins called TDP-43 accumulated in the motor areas of the brains of patients with amyotropic lateral sclerosis (ALS), or Lou Gehrig's disease.

Potential in yeast for selecting Lou Gehrig's disease drugs

harminka — Fri, 18 Apr 2008 05:31:51 -0500

Researchers from the University of Pennsylvania School of Medicine are developing a novel approach to screen for drugs to combat neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS), or Lou Gehrig's disease, using yeast cells. In recent months a number of mutations have been found in a disease protein called TDP-43, which is implicated in ALS and certain types of frontotemporal dementia (FTD).

Understanding Noxious cause of Lou Gehrig's disease

harminka — Fri, 14 Sep 2007 12:59:19 -0500

There is no known cure for amyotrophic lateral sclerosis (ALS), often known as Lou Gehrig disease and motor neuron disease. ALS is a progressive, fatal, neurodegenerative disease caused by the degeneration of nerves that control voluntary muscle movement.

Stem cell therapy rescues motor neurons in ALS model

harminka — Wed, 01 Aug 2007 01:12:02 -0500

In a study that demonstrates the promise of cell-based therapies for diseases that have proved intractable to modern medicine, a team of scientists from the University of Wisconsin-Madison has shown it is possible to rescue the dying neurons characteristic of amyotrophic lateral sclerosis (ALS), a fatal neuromuscular disorder also known as Lou Gehrig's disease.

Seeking cure for Lou Gehrig's disease

harminka — Mon, 30 Jul 2007 10:44:47 -0500

A small tropical fish, the curiosity of a Geisinger research scientist and some college students have created the perfect storm of sorts in an attempt to find a cure for one of the world’s most devastating neurological diseases.

New tool for studying disease and identifying ALS drugs

harminka — Mon, 16 Apr 2007 11:46:14 -0500

Results of two studies funded by Project A.L.S. and appearing in today's advance online publication of Nature Neuroscience demonstrate that embryonic stem cells may provide a new tool for studying disease mechanisms and for identifying drugs to slow ALS, also known as Lou Gehrig's disease.