myelin production

Human ES cells progress slowly in myelin's direction

harminka — Thu, 09 Apr 2009 07:14:32 -0500

Scientists from the University of Wisconsin, USA, report in the journal Development (dev.biologists.org) the successful generation from human embryonic stem cells of a type of cell that can make myelin, a finding that opens up new possibilities for both basic and clinical research.

CXCL1 Decreases Severity of Multiple Sclerosis-like disease

harminka — Tue, 30 Dec 2008 15:29:00 -0600

A group led by Dr. Cedric Raine at Albert Einstein College of Medicine have explored the expression of an immune molecule (CXCL1) that interacts with myelin-producing cells, finding that CXCL1 decreases the severity of disease in a mouse model of multiple sclerosis (MS).

Claudin 11 stops the leaks in neuronal myelin sheaths

harminka — Mon, 01 Dec 2008 13:00:27 -0600

Devaux and Gow demonstrate how a tight junction protein called claudin 11 makes the neuronal myelin sheath a snug fit. The study will be published in the December 1, 2008 issue of the Journal of Cell Biology (www.jcb.org).

Researchers discover gene crucial for nerve cell insulation

harminka — Tue, 17 Apr 2007 10:54:29 -0500

Researchers funded by the National Institutes of Health have discovered how a defect in a single master gene disrupts the process by which several genes interact to create myelin, a fatty coating that covers nerve cells and increases the speed and reliability of their electrical signals.