fibrosis

Therapeutic agent for hepatic fibrosis found

harminka — Wed, 26 Aug 2009 08:06:23 -0500

Accumulating evidence suggests that connective tissue growth factor (CCN2) plays a central role in fibrotic conditions in many organ systems. Fibrosis is a scarring condition that is characterized by excessive collagen production that impedes normal cell function and can cause organ dysfunction and failure.

Scientists identify novel way to prevent cardiac fibrosis

harminka — Wed, 23 Apr 2008 09:49:32 -0500

In a study that points to a new strategy for preventing or possibly reversing fibrosis – the scarring that can lead to organ and tissue damage – researchers at the University of California, San Diego School of Medicine have determined that a molecule called Epac (Exchange protein activated by cAMP1), plays a key role in integrating the body’s pro- and anti-fibrotic response.

Serum fibrosis markers correlate with liver fibrosis stage in patients with hepatitis C

harminka — Mon, 03 Mar 2008 13:20:00 -0600

A prospective study of patients with advanced chronic hepatitis C (CHC) revealed that a 3-variable model of serum fibrosis markers, including serum HA, TIMP-1 and platelet count, could identify cirrhosis with better accuracy than other published models.

Fibrosis can be stopped, cured and reversed

harminka — Thu, 27 Dec 2007 08:24:30 -0600

University of California, San Diego researchers have proven in animal studies that fibrosis in the liver can be not only stopped, but reversed.

Carbon monoxide counteracts one side-effect of anti-cancer drug

harminka — Fri, 23 Nov 2007 12:38:22 -0600

Doxorubicin (DOX) is a red-colored anticancer drug that carries serious side effects for the heart, including cardiac muscle deterioration (cardiomyopathy) and scar tissue accumulation in the heart (fibrosis).

Noninvasive tests for cirrhosis may help to avoid liver biopsy

harminka — Mon, 01 Oct 2007 13:57:14 -0500

Newer ultrasound and magnetic resonance (MR) imaging tests yield encouraging initial results in diagnosing fibrosis (scarring) and cirrhosis of the liver, according to three studies in the October issue of the journal Clinical Gastroenterology and Hepatology.

Hhigh mortality rates from pulmonary fibrosis will continue to rise

harminka — Thu, 02 Aug 2007 01:09:31 -0500

Mortality rates from pulmonary fibrosis (PF) have increased significantly in recent years, and are predicted to continue to rise, according to researchers from the University of Colorado.

Test to identify breast cancer patients reacting badly to radiotherapy

harminka — Thu, 19 Apr 2007 11:18:03 -0500

Medical scientists at the University of Leicester have announced a potentially unique advance in breast cancer research by identifying two genes associated with adverse reaction to cancer treatment.