blood disorders

Pesticides Appliers Have Double Risk of Blood Disorder

harminka — Sat, 13 Jun 2009 01:58:25 -0500

A study involving 678 individuals who apply pesticides, culled from a U.S. Agricultural Health Study of over 50,000 farmers, recently found that exposure to certain pesticides doubles one's risk of developing an abnormal blood condition called MGUS (monoclonal gammopathy of undetermined significance) compared with individuals in the general population.

Genetic abnormality may increase risk of blood disorders

harminka — Mon, 16 Mar 2009 06:12:31 -0500

Researchers at Memorial Sloan-Kettering Cancer Center (MSKCC) have shown for the first time that a tendency to develop some blood disorders may be inherited.

Anti-clotting drug thins risk to pregnancy and surgery patients with blood disorder

harminka — Tue, 09 Dec 2008 05:19:37 -0600

Pregnancy and surgery patients with a serious blood disorder that causes excessive clotting have responded well to treatment with a man-made anti-clotting protein. Results from a study by researchers at Yale School of Medicine and other institutions were presented December 6 at the Annual Meeting of the American Society of Hematology (ASH) in San Francisco.

Scientists shed light on evolution of gene regulation

harminka — Tue, 25 Nov 2008 14:16:30 -0600

Scientists at Penn State have shed light on some of the processes that regulate genes -- such as the processes that ensure that proteins are produced at the correct time, place, and amount in an organism -- and they also have shed light on the evolution of the DNA regions that regulate genes.

Avoiding Spleen Removal for Cooley's Anemia Sufferers

harminka — Tue, 27 May 2008 14:20:24 -0500

Researchers from Weill Cornell Medical College may have discovered the precise role of a gene in one of the world's most common blood disorders, beta-thalassemia, commonly known as Cooley's anemia. Along with sickle-cell anemia, Cooley's anemia is the most commonly inherited disease in the world, affecting many people of Mediterranean descent, and 20 out of every 100,000 African-Americans.

Importamt role of Teamwork between 2 key proteins

harminka — Mon, 06 Aug 2007 13:07:38 -0500

Virginia Commonwealth University researchers studying hemoglobin genes, mutations of which play a role in genetic blood disorders like sickle cell anemia and beta-thalassemia, have identified two proteins that are responsible for regulating overlapping groups of genes during the development of red blood cells.

Too much or too little underlies sex abnormalities

harminka — Sat, 28 Jul 2007 01:37:44 -0500

6% of the patient population in Melbourne carries a genetic abnormality implicated in thalassemia. As well as causing blood disorders and severe mental retardation, boys with ATRX mutations have genital abnormalities.

Keeping red blood cells hydrated in sickle cell disease

harminka — Sat, 19 May 2007 04:32:30 -0500

Sickle cell anemia is the most common inherited blood disorder in the United States. The transport of potassium (K) and chloride (Cl) ions in and out of red blood cells is a major determinant of the cells' volume and density. Overactivation of K-Cl cotransport out of red blood cells leads to red blood cell dehydration and distortion (sickling).