H. pylori infection

Estrogen receptor isoforms expression in stomach of Mongolian gerbils

harminka — Sat, 01 Nov 2008 04:05:25 -0500

We have previously shown that E2 and P4 have clear and distinct effects on inflammatory response and gastric epithelial changes during early H. pylori infection. Recently, Ohtani et al., have shown a protective role of E2 administration in H. pylori-infected InGas mice.

hefA plays important role in multidrug resistance of Helicobacter pylori

harminka — Sat, 20 Sep 2008 08:45:31 -0500

Three RND efflux systems had been identified in H pylori, namely hefABC, hefDEF, and hefGHI, each of which consisted of a translocase, an accessory protein.

Serology test or C14-urea breath test, which is more accurate

harminka — Wed, 10 Sep 2008 07:08:16 -0500

Serology and C14-UBT are the most commonly used non-invasive tests of H. pylori infection. The diagnostic characteristics of the tests depend also on the prevalence of H. pylori infection in the population tested. The diagnostic characteristics of the tests depend also on the prevalence of H. pylori infection in the population tested.

How do Lactobacilli treat Helicobacter pylori-related diseases?

harminka — Wed, 10 Sep 2008 06:43:25 -0500

Some studies have demonstrated H. pylori stimulates the release of interleukin-8 (IL-8) from gastric epithelia, which initiates inflammatory damage to gastric mucosa and plays a crucial role in the pathogenesis of H. pylori infections. H. pylori lipopolysaccharide (H. pylori-LPS) is the major initiator in H. pylori-induced IL-8 production via activation of Toll-like receptor 4 (TLR4) pathway in gastric epithelia.

Stomach bug appears to protect kids from asthma, says NYU study

harminka — Tue, 15 Jul 2008 08:42:36 -0500

A long-time microbial inhabitant of the human stomach may protect children from developing asthma, according to a new study among more than 7,000 subjects led by NYU Langone Medical Center researchers. Helicobacter pylori, a bacterium that has co-existed with humans for at least 50,000 years, may lead to peptic ulcers and stomach cancer.

Early treatment of stomach infection may prevent cancer

harminka — Thu, 01 May 2008 01:15:08 -0500

Based on research using a new mouse model of gastritis and stomach cancer, researchers from the Massachusetts Institute of Technology (MIT) say that prompt treatment of Helicobacter pylori (H. pylori) infections reverses damage to the lining of the stomach that can lead to cancer.

Gastric juice for diagnosis of H. pylori infection

harminka — Wed, 30 Apr 2008 15:04:40 -0500

This study determined the efficiency of a gastric juice PCR test for the detection of H. pylori infection in patients receiving PPI therapy and compared it with histology and gastric biopsy PCR.

H. pylori inhibits intercellular communication of cultured gastric cells

harminka — Sat, 27 Oct 2007 14:37:25 -0500

The formation of a cancer is proven to be a multi-stage, multi-mechanism process by animal and human studies. As a definite carcinogen, the role of Helicobacter pylori (H pylori) in the formation of gastric cancer has been unclear.

Low prevalence of H pylori in HIV-positive patients

harminka — Tue, 16 Oct 2007 15:53:36 -0500

Helicobacter pylori has been extensively studied and proven to be the main cause of chronic gastritis and peptic ulcer in the HIV-negative population. Patients with chronic active gastritis have evidence of H pylori infection in over 90% of cases and in 70-100% of those with peptic ulcer disease.

Salt increases risk of gastric disease

harminka — Wed, 23 May 2007 03:45:57 -0500

Scientists have identified yet another risk from a high-salt diet. High concentrations of salt in the stomach appear to induce gene activity in the ulcer-causing bacterium Helicobacter pylori, making it more virulent and increasing the likelihood of an infected person developing a severe gastric disease.