Tuberculosis treatment

How to prevent liver damage induced by anti-tuberculosis treatment?

harminka — Sat, 20 Sep 2008 01:07:29 -0500

About one third of the world's population has latent tuberculosis and roughly 9 million cases of active tuberculosis emerge annually resulting in 2-3million deaths. Most new cases occur in the most populated nations like India and China.

Certain HIV treatment less effective when used with anti-Tuberculosis therapy

harminka — Sun, 03 Aug 2008 13:24:15 -0500

Patients receiving rifampicin-based anti-tuberculosis therapy are more likely to experience virological failure when starting nevirapine-based antiretroviral therapy, an HIV treatment that is widely used in developing countries because of lower cost, than when starting efavirenz-based antiretroviral therapy, according to a study in the August 6 issue of JAMA, a theme issue on HIV/AIDS.

Strategies to control tuberculosis outdated, inadequate

harminka — Fri, 01 Aug 2008 09:26:29 -0500

The standard regimens to treat tuberculosis (TB) are inadequate in countries with high rates of multi-drug resistant (MDR) TB. In countries with high rates of MDR-TB, patients are nearly twice as likely to fail their initial treatment than those in countries with low rates, according to a new analysis of World Health Organization (WHO) data.

Potential new drug target to fight tuberculosis identified

harminka — Thu, 31 Jul 2008 11:02:14 -0500

With antibiotic resistance on the rise, tuberculosis is emerging as a bigger global health threat than ever before.

Which populations of foreign-born persons living in US at higher risk of TB

harminka — Wed, 23 Jul 2008 08:21:01 -0500

The relative yield of finding and treating latent tuberculosis is particularly high among higher-risk groups of foreign-born persons living in the U.S., such as individuals from most countries of sub-Saharan Africa and Southeast Asia, according to a study in the July 23/30 issue of JAMA.

Excavated Jericho bones may help to combat tuberculosis

harminka — Mon, 14 Jul 2008 11:16:15 -0500

Six-thousand year old bones excavated in Jericho may help a joint Israeli-Palestinian-German research group combat tuberculosis.

Arizona State University research team working to decode Tuberculosis

harminka — Tue, 08 Jul 2008 13:21:15 -0500

Tuberculosis may call to mind Old West consumptives and early 20th-century sanatoriums, yet according to the World Health Organization, the disease took the lives of more than 1.5 million people worldwide in 2006.

How can we overcome barriers to treating drug-resistant tuberculosis?

harminka — Tue, 08 Jul 2008 13:01:33 -0500

Almost 1 in 20 cases of tuberculosis worldwide is resistant to multiple drugs (known as multidrug-resistant TB or MDR-TB) and the World Health Organization has called for a massive scale up in public health efforts to tackle these cases.

Potential treatment for tuberculosis solves puzzle

harminka — Fri, 04 Jul 2008 02:30:28 -0500

Scientists have uncovered a new target for the potential treatment of TB, finally resolving a long-running debate about how the bacterial cell wall is built. The research, published in the July issue of Microbiology reveals several molecules that could be developed into drugs to treat tuberculosis.

Source of drug-tolerant tuberculosis possibly behind TB relapses

harminka — Thu, 12 Jun 2008 07:52:33 -0500

University of Pittsburgh-led researchers discovered that the primary bacteria behind tuberculosis can grow on surfaces and that drug-tolerant strains flourish in these bacterial communities, the research team recently reported in “Molecular Microbiology.”

Latent tuberculosis treatment saves time money and lives

harminka — Tue, 20 May 2008 12:59:08 -0500

A new way to treat patients with latent tuberculosis (TB), who are infected with TB but without symptoms, can effectively treat it in less than half the time and at a lower cost than the current standard treatment, according to researchers who conducted a multi-center, randomized controlled trial. The results will be presented at the American Thoracic Society’s 2008 International Conference in Toronto on Tuesday, May 20.

Elucidating iron transport mechanisms in tuberculosis bug identifies new TB drug targets

harminka — Wed, 07 May 2008 00:15:09 -0500

It is pathetically true that Mycobacterium tuberculosis, the causative agent of TB is still thriving the test of scientific interventions despite affecting almost one -third of the worlds’ population. The fact that it takes approximately one human life every 15 second somewhere in the world is an unfortunate death statistics unmatched by any other microbe.