aging disorder

Anti-cancer drug prevents cardiovascular damage of premature aging disorder

harminka — Tue, 07 Oct 2008 01:14:12 -0500

An experimental anti-cancer drug can prevent -- and even reverse -- potentially fatal cardiovascular damage in a mouse model of progeria, a rare genetic disorder that causes the most dramatic form of human premature aging, National Institutes of Health (NIH) researchers reported today.

Healthier mouse that could hold clues to human aging

harminka — Mon, 22 Oct 2007 14:39:56 -0500

A study by scientists at UCL (University College London) shows that mice lacking the insulin receptor substrate (IRS)-1 are more resistant to ageing than normal mice. The research adds to a growing body of work showing the importance of insulin signalling pathways as an ageing mechanism in mammals – and potentially humans.

Aging stem cells hold answers to diseases of aged

harminka — Thu, 07 Jun 2007 00:27:17 -0500

As stem cells in the blood grow older, genetic mutations accumulate that could be at the root of blood diseases that strike people as they age, according to work done in mice by researchers at the Stanford University School of Medicine.