neuroblastoma

PET May Guide Pediatric Cancer Treatment

harminka — Mon, 03 Aug 2009 08:01:47 -0500

A new study published in the August issue of The Journal of Nuclear Medicine shows that positron emission tomography (PET) is an important tool for depicting the extent of neuroblastoma in some patients, particularly for those in the early stages of the disease.

Genetic Finding Promises Targeted Therapy for Neuroblastoma

harminka — Wed, 24 Jun 2009 11:57:08 -0500

Researchers have identified a genetic glitch that could lead to development of neuroblastoma, a deadly form of cancer that typically strikes children under 2.

Genome Research Unlocking Secrets of Neuroblastoma

harminka — Wed, 17 Jun 2009 13:47:38 -0500

Two new studies from The Children's Hospital of Philadelphia advance the search for genetic events that result in neuroblastoma, a puzzling, often-deadly type of childhood cancer.

Drug inhibits neuroblastoma blood supply in pre-clinical tests

harminka — Fri, 24 Apr 2009 12:01:18 -0500

Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have found a way to prevent blood vessels from aiding the growth of neuroblastoma, a childhood cancer. The pre-clinical study was presented today in a platform session at the 22nd annual meeting of the American Society of Pediatric Hematology/Oncology.

New cancer drug reduces neuroblastoma growth by 75 percent

harminka — Fri, 24 Apr 2009 02:22:03 -0500

Researchers from the Children's Cancer Hospital at The University of Texas M. D. Anderson Cancer Center have found a new drug that restricts the growth of neuroblastoma, a childhood brain cancer.

Engineered virus targets and kills apparent cancer stem cells in neuroblastoma

harminka — Wed, 21 Jan 2009 05:12:03 -0600

After identifying an apparent population of cancer stem cells for neuroblastoma, researchers successfully used a reprogrammed herpes virus to block tumor formation in mice by targeting and killing the cells.

New insight into aggressive childhood cancer

harminka — Mon, 05 Jan 2009 13:48:11 -0600

A new study reveals critical molecular mechanisms associated with the development and progression of human neuroblastoma, the most common cancer in young children.

Double-barreled immune cell approach for neuroblastoma

harminka — Mon, 03 Nov 2008 11:42:57 -0600

Adding an artificial tumor-specific receptor to immune system cells called T-lymphocytes that target a particular virus extended and improved the cells' ability to fight a form of childhood cancer called neuroblastoma, said researchers form Baylor College of Medicine and Texas Children's Hospital in a report that appears online today in the journal Nature Medicine.

Researchers identify promising gene target for neuroblastoma therapy

harminka — Thu, 16 Oct 2008 00:47:50 -0500

Researchers at Dana-Farber Cancer Institute have identified a set of previously unknown mutations in a single gene in 8 percent of neuroblastomas, tumors of the nervous system that occur in young children and account for approximately 15 percent of all childhood cancer deaths.

Researchers develop novel anti-tumor vaccine

harminka — Fri, 03 Oct 2008 02:03:08 -0500

New mouse model uncovers more effective delivery of anti-tumor vaccines for neuroblastoma and melanoma

Gene that causes childhood cancer neuroblastoma is found

harminka — Mon, 25 Aug 2008 14:16:08 -0500

Scientists have discovered gene mutations that are the main cause of the inherited version of the childhood cancer neuroblastoma. In addition, the researchers found that the same mutations play a significant role in high-risk forms of non-inherited neuroblastoma, the more common form of the disease.

Tumor Suppressor Gene Identification Associated with Patient Outcome in Neuroblastoma

harminka — Wed, 25 Jun 2008 04:27:07 -0500

Expression of the CHD5 gene is frequently down-regulated in neuroblastomas, and patients whose tumors lacked CHD5 expression were more likely to have shorter event-free and overall survival compared with patients whose tumors expressed CHD5.