ankylosing spondylitis

Adalimumab therapy effective in ankylosing spondylitis

harminka — Thu, 12 Jun 2008 09:14:24 -0500

Adalimumab therapy is effective and well-tolerated in ankylosing spondylitis (AS), rheumatoid arthritis (RA) and psoriatic arthritis (PsA) patients with a previously inadequate response to anti-tumour necrosis factor (anti-TNF) therapies etanercept and infliximab, according to results of research presented today at EULAR 2008, the Annual European Congress of Rheumatology in Paris, France.

Golimumab reduces signs, symptoms of ankylosing spondylitis

harminka — Thu, 08 Nov 2007 02:25:11 -0600

More than half of patients receiving monthly subcutaneous (SC) injections of golimumab (CNTO 148) 50 mg and 100 mg experienced significant and sustained improvements in the signs and symptoms of active ankylosing spondylitis, according to Phase 3 study results presented at the American College of Rheumatology (ACR) annual meeting.

Rheumatologists Discover Two Genes Related to Disabling Form of Arthritis

harminka — Sun, 21 Oct 2007 13:36:28 -0500

Work done in part by researchers at The University of Texas Medical School at Houston has led to the discovery of two genes that cause ankylosing spondylitis, an inflammatory and potentially disabling disease. The findings are published in the Oct. 21 online edition of Nature Genetics, a journal that emphasizes research on the genetic basis for common and complex diseases.

Major genetic breakthrough for ankylosing spondylitis brings treatment hope

harminka — Sun, 21 Oct 2007 13:31:30 -0500

Research funded by the Wellcome Trust and the Arthritis Research Campaign has identified two genes implicated in the disease ankylosing spondylitis, a common disease primarily causing back pain and progressive stiffness. The research, published online today in Nature Genetics, suggests that a treatment currently being trialled for Crohn's disease may also be applied to this disease.

Study reveals 2 genes linked to disabling arthritis

harminka — Sun, 21 Oct 2007 13:27:27 -0500

An international team of researchers led by a Fred Hutchinson Cancer Research Center geneticist has discovered two genes linked to a disabling form of arthritis called ankylosing spondylitis, a painful and progressive disease in which some or all of the spine’s vertebrae fuse together.

Common genetic background for ankylosing spondylitis and inflammatory bowel disease

harminka — Mon, 30 Jul 2007 06:46:07 -0500

Researchers and clinicians have widely noted an intriguing link between some intestinal diseases and some forms of arthritis. In particular, chronic inflammatory bowel disease (IBD) frequently afflicts patients with ankylosing spondylitis (AS), marked by chronic inflammation of the spine and the sacroiliac joints. Separately, both IBD and AS have been shown to run in families.

Data showing improvement in spinal mobility, spinal inflammation

harminka — Wed, 20 Jun 2007 07:19:53 -0500

Data presented at the European League Against Rheumatism (EULAR) Annual European Congress of Rheumatology showed that patients with ankylosing spondylitis (AS) who received REMICADEÃ‚Â® (infliximab) over two years experienced significant improvement in spinal mobility.