drugs side effects

Antidepressant No More Effective Than Placebo For Autistic Children

Margaret Wilde — Tue, 02 Jun 2009 06:27:08 -0500

A government-funded study involving 149 participants aged 5 to 17 finds that the antidepressant, Citalopram, is no more effective than a placebo and has side-effects twice as bad. About a third of autistic children in the US take this drug or others closely related to it.

Some Elderly Patients Are At Risk Due To Dementia drugs

harminka — Thu, 28 May 2009 03:33:05 -0500

Side effects associated with several commonly-prescribed dementia drugs may be putting elderly Canadians at risk, says Queen's University Geriatrics professor Sudeep Gill.

Profound effects of numbing agents

harminka — Fri, 12 Dec 2008 15:16:59 -0600

A large proteomics study on the brains of newborn mice provides more evidence that numbing drugs often used in obstetric or pediatric medicine can have profound and long-term negative effects, even after minimal exposure.

First-ever genetic models predict effects of anesthetic agents

harminka — Mon, 27 Oct 2008 13:42:46 -0500

Researchers at Rhode Island Hospital have created the first animal model that can reveal the side effects of anesthetic agents (the substances used to block pain during surgery) in individuals genetically predisposed to sudden cardiac death.

Side effects of monotherapy with lamivudine

harminka — Wed, 24 Sep 2008 10:56:01 -0500

Lamivudine has a high rate of antiviral resistance. Sequential anti-HBV treatment is commonly used for lamivudine resistance. We report 4 cases with rapid re-detection of HBV mutants during the lamivudine re-treatment.

ESF study helps stop drugs slipping through safety net

harminka — Tue, 16 Sep 2008 13:10:01 -0500

Recent advances in genetic screening will lead to safer pharmaceutical drugs, with reduced adverse side effects, if the methods are incorporated in clinical development.

How a tiny protein senses all the communications in cell

harminka — Thu, 31 Jul 2008 13:42:13 -0500

Cells rely on calcium as a universal means of communication. For example, a sudden rush of calcium can trigger nerve cells to convey thoughts in the brain or cause a heart cell to beat. A longstanding mystery has been how cells and molecules manage to appropriately sense and respond to the variety of calcium fluctuations within cells

Increasingly potent drug ingredients offer growing market as manufacturers address worker safety

harminka — Mon, 16 Jun 2008 08:44:07 -0500

To develop improved drugs for fighting cancer and other diseases, pharmaceutical researchers are finding increasingly potent drug ingredients that will allow smaller doses while causing fewer side effects, according to an article scheduled for the June 16 issue of Chemical & Engineering News.

Duke chemist has new way to tell right from left

harminka — Fri, 06 Jun 2008 10:53:59 -0500

A Duke University chemist has apparently solved a long-standing frustration in creating certain synthetic molecules that make up drugs, which could lead to better drugs with fewer side effects.

New computational technique can predict drug side effects

harminka — Wed, 12 Dec 2007 11:29:09 -0600

Early identification of adverse effects of drugs before they are tested in humans is crucial in developing new therapeutics, as unexpected effects account for a third of all drug failures during the development process.

Women stop taking breast cancer drug because of side effects

harminka — Thu, 06 Sep 2007 01:08:13 -0500

More than 10 percent of women with breast cancer stopped taking a commonly prescribed drug because of joint and muscle pain, according to a new study from researchers at the University of Michigan Comprehensive Cancer Center.

New study may explain Vioxx side-effects

harminka — Mon, 27 Aug 2007 12:40:24 -0500

Vioxx and related pain medications were taken off the market in 2004 because they caused dangerous heart problems in some people. A group of scientists, led by Timothy Hla at the University of Connecticut, may now have figured out how these drugs trigger these life-threatening side-effects.