Huntington’s disease

Mechanism of action of antibiotic able to reduce neuronal cell death in brain

harminka — Sat, 10 May 2008 04:18:48 -0500

Virginia Commonwealth University researchers have discovered how an antibiotic works to modulate the activity of a neurotransmitter that regulates brain functions, which eventually could lead to therapies to treat Alzheimer’s disease, Huntington’s disease, epilepsy, stroke, dementia and malignant gliomas.

New stem cell technique improves genetic alteration

harminka — Sat, 08 Mar 2008 13:59:23 -0600

UC Irvine researchers have discovered a dramatically improved method for genetically manipulating human embryonic stem cells, making it easier for scientists to study and potentially treat thousands of disorders ranging from Huntington’s disease to muscular dystrophy and diabetes.

Iron banded worms drying out of blood could be linked to Parkinson's and Alzheimer's

harminka — Sat, 09 Feb 2008 11:49:16 -0600

Researchers at the University of Warwick and the Indian Institute of Technology Kanpur have discovered that the mechanism that we rely on to transport iron safely through our blood stream can, in certain circumstances, collapse into a state which grows long worm-like “fibrils” banded by lines of iron rust. This process could provide the first insight into how iron gets deposited in the brain to cause some forms of Parkinson’s & Alzheimer’s and Huntington’s diseases.

Huntington's disease problem start early

harminka — Wed, 09 Jan 2008 14:15:49 -0600

The damaging effects of the mutated protein involved in Huntington’s disease take place earlier in cell life than previously believed, said researchers from Baylor College of Medicine in Houston in a report that appears in the current edition of the journal Neuron.

Study suggests new treatments for Huntington's disease

harminka — Wed, 09 Jan 2008 14:06:35 -0600

Working with fruit flies, researchers have discovered a new mechanism by which the abnormal protein in Huntington’s disease causes neurodegeneration.

Study identifies potential treatment for Huntington's disease

harminka — Tue, 09 Oct 2007 06:59:15 -0500

MassGeneral Institute for Neurodegererative Disorders (MIND) researchers have identified a compound that may lead to a treatment that could protect against the effects of Huntington’s Disease (HD). Their report, which will appear in the Proceedings of the National Academy of Sciences, describes how a small molecule called C2-8 appears to delay the loss of motor control and reduce neurological damage in a mouse model of the disorder.

Biologists link Huntington's disease to health benefits in young

harminka — Wed, 26 Sep 2007 10:16:47 -0500

For years researchers in neurology have believed that people with Huntington’s disease have more children than the general population because of behavioral changes associated with the disease that lead to sexual promiscuity.

Stem cells show promise for treating Huntington's disease

harminka — Tue, 25 Sep 2007 23:51:06 -0500

Paying close attention to how a canary learns a new song has helped scientists open a new avenue of research against Huntington’s disease – a fatal disorder for which there is currently no cure or even a treatment to slow the disease.

Schizophrenia improved by mental and physical exercise

harminka — Fri, 03 Aug 2007 09:38:58 -0500

Scientists at Melbourne's Howard Florey Institute have shown that mental and physical exercise can improve behavioural deficits in schizophrenia and repair damaged chemical transmitter pathways in the brain.

Huntington's disease study shows animal models on target

harminka — Wed, 01 Aug 2007 01:38:44 -0500

An international team of researchers has published a benchmark study showing that gene expression in several animal models of Huntington’s Disease (HD) closely resembles that of human HD patients.

Drug protects brain cells in Huntington's disease model

harminka — Wed, 25 Jul 2007 05:17:35 -0500

A drug used in some countries to treat the symptoms of Huntington’s disease prevents death of brain cells in mice genetically engineered to mimic the hereditary condition, UT Southwestern Medical Center researchers have found.