Alzheimer's disease

Improving memory in Alzheimer's disease mice

harminka — Wed, 02 Jul 2008 06:56:49 -0500

Overactivation of proteins known as calpains, which are involved in memory formation, has been linked to Alzheimer disease.

Good and bad of a potential Alzheimer's target

harminka — Sat, 28 Jun 2008 05:19:59 -0500

Research in fruit flies has shown that enhancing the production of a protein called neprilysin can reduce the formation of plaques and neuron death associated with Alzheimer's, at the expense of reducing the flies' lifespan.

Alzheimer's disease as a case of brake failure?

harminka — Wed, 25 Jun 2008 07:46:35 -0500

Rutgers researcher Karl Herrup and colleagues at Case Western Reserve University have discovered that a protein that suppresses cell division in brain cells effectively "puts the brakes" on the dementia that comes with Alzheimer's disease (AD). When the brakes fail, dementia results.

Anti-inflammatory drug blocks brain plaques

harminka — Tue, 24 Jun 2008 08:36:55 -0500

Brain destruction in Alzheimer's disease is caused by the build-up of a protein called amyloid beta in the brain, which triggers damaging inflammation and the destruction of nerve cells. Scientists had previously shown that preventing individual amyloid beta proteins from sticking to one another minimized brain lesions and protected nerve cells against damage.

Automated MRI technique assists in earlier Alzheimer's diagnosis

harminka — Tue, 24 Jun 2008 02:18:15 -0500

An automated system for measuring brain tissue with magnetic resonance imaging (MRI) can help physicians more accurately diagnose Alzheimer's disease at an earlier stage according to a new study published in the July issue of the journal Radiology.

Known genetic risk for Alzheimer's in whites also places blacks at risk

harminka — Thu, 19 Jun 2008 13:59:22 -0500

A commonly recognized gene that places one at risk for Alzheimer's disease does not discriminate between blacks and whites, according to new research led by Florida State University.

Potential new role for red grape seeds in treatment of Alzheimer's disease

harminka — Wed, 18 Jun 2008 08:08:21 -0500

Mount Sinai researchers have discovered that polyphenolics derived from red grape seeds may be useful agents to prevent or treat Alzheimer's disease (AD).

Researchers are quick study when assessing drugs for Alzheimer's disease

harminka — Mon, 16 Jun 2008 13:07:14 -0500

Researchers are actively cutting the time and cost it normally takes to develop radiopharmaceuticals by taking advantage of "Exploratory Investigational New Drug" (ExpIND), an FDA-sanctioned procedure that enhances post-discovery drug development while observing scientific and patient safety standards.

Molecular imaging sheds new light on progression of Alzheimer's disease

harminka — Mon, 16 Jun 2008 11:42:17 -0500

In the past, physicians were able only to follow the progression of Alzheimer's disease (AD) through careful clinical histories, noting the often subtle changes associated with cognitive decline over a number of years.

Stem cell researchers give old muscle new pep

harminka — Sun, 15 Jun 2008 12:30:37 -0500

Old muscle got a shot of youthful vigor in a stem cell experiment by bioengineers at the University of California, Berkeley, setting the path for research on new treatments for age-related degenerative conditions such as muscle atrophy or Alzheimer's and Parkinson's diseases.

Increases in TST improve cognition in Alzheimer patients with OSA

harminka — Wed, 11 Jun 2008 00:17:24 -0500

Increases in total sleep time related to the treatment of obstructive sleep apnea (OSA) with continuous positive airway pressure (CPAP) are associated with improvements in cognition in patients with Alzheimer disease, according to a research abstract that will be presented on Tuesday at SLEEP 2008, the 22nd Annual Meeting of the Associated Professional Sleep Societies (APSS).

No advantage of A42-lowering NSAIDs for prevention of Alzheimer dementia

admin_huliq — Thu, 29 May 2008 06:57:35 -0500

The research, published in the journal Neurology suggests that people who took NSAIDs, the drug group which aspirin and ibuprofen belong to, have a more than 20 per cent reduced risk of developing Alzheimer.