anti-cancer drugs

Synthetic molecules hold promise for new family of anti-cancer drugs

harminka — Wed, 04 Jun 2008 14:42:42 -0500

Synthetic molecules designed by two Hebrew University of Jerusalem researchers have succeeded in reducing and even eliminating the growth of human malignant tissues in mice, while having no toxic effects on normal tissue.

Fireflies' glow helps UT Southwestern researchers track cancer drug's effectiveness

harminka — Thu, 29 May 2008 07:15:58 -0500

The gene that allows fireflies to flash is helping researchers track the effectiveness of anti-cancer drugs over time.

Study calls for action on heart risks from certain anti-cancer drugs

harminka — Mon, 28 Apr 2008 08:19:04 -0500

Heart damage from certain anti-cancer drugs no longer should be regarded as a rare or relatively unimportant complication, scientists in Italy have concluded in a new overview of research on the cardiotoxicity of anti-cancer drugs.

Study reveals basis of anticancer drug resistance in childhood leukemia

harminka — Wed, 16 Apr 2008 05:55:47 -0500

The first analysis of the genetic determinants of resistance to the anti-cancer drug methotrexate in childhood acute lymphoblastic leukemia (ALL) could offer a pathway to predicting such resistance and treatments to overcome it, according to a St. Jude Children’s Research Hospital study.

Dealing deadly cancers a knockout punch

harminka — Thu, 10 May 2007 07:55:28 -0500

New scientific evidence is helping to build a compelling case for oncolytic viruses as a first-line and adjunctive treatment for many cancers.

Effective drug against drug-resistant cancer cells

harminka — Wed, 02 May 2007 07:07:22 -0500

A new study highlighted on the cover of this week's issue of Cancer Research finds that the anti-cancer drug GleevecÃ‚Â® is far more effective against a drug-resistant strain of cancer when the drug wraps the target with a molecular bandage that seals out water from a critical area. The research appears as a priority report in the journal's May 1 issue.

New mechanism identified for resistance to targeted lung cancer drugs

harminka — Fri, 27 Apr 2007 02:37:30 -0500

An international research team, led by investigators from the Massachusetts General Hospital (MGH) Cancer Center and Dana-Farber Cancer Institute (DFCI), has found a new way that some lung tumors become resistant to treatment with targeted therapy drugs like Iressa and Tarceva.

Why cisplatin kills breast cancer cells when other drugs fail

harminka — Fri, 20 Apr 2007 01:55:17 -0500

The cancerous cells of some individuals with breast cancer lack expression of two cell surface proteins, the estrogen and progesterone receptors, and do not express increased amounts of HER2. Individuals with such breast cancer (known as triple-negative breast cancer) do not respond to treatment with commonly used chemotherapeutic drugs and their prognosis is relatively poor.

New protein-targeted drug inhibited growth of human lung and colon cancer cells

harminka — Mon, 16 Apr 2007 11:19:27 -0500

Integrating the use of drugs targeted to specific cancer proteins into current chemotherapy regimens to improve the efficacy of systemic treatment is an important clinical goal at Fox Chase Cancer Center.

Key protein identified to breast cancer spread

harminka — Tue, 10 Apr 2007 00:23:19 -0500

Researchers at the Kimmel Cancer Center at Jefferson have identified a protein that they say is key to helping a quarter of all breast cancers spread. The finding, reported online the week of April 9, 2007 in the journal Proceedings of the National Academy of Sciences, could be a potential target for new drugs aimed at stopping or slowing the growth and progression of breast cancer.

New cancer drugs show progression of recurrent prostate cancer

harminka — Sat, 17 Feb 2007 07:32:55 -0600

New reason why patients respond differently to the same drug dose

harminka — Mon, 15 Jan 2007 09:10:58 -0600