chemotherapy

Prostate cancer drug reverses resistance to chemotherapy

harminka — Thu, 24 Sep 2009 07:40:56 -0500

For the first time researchers have shown that by inhibiting the action of an enzyme called TAK-1, it is possible to make pancreatic cancer cells sensitive to chemotherapy, opening the way for the development of a new drug to treat the disease.

Researchers inhibit cancer proteins

harminka — Thu, 20 Aug 2009 11:14:22 -0500

A research team led by U of T Mississauga scientists has developed a new way to split up a dangerous pair of cancer proteins, a finding that could ultimately lead to chemotherapy that is more effective and has fewer side effects.

How cancer cells respond to chemotherapy

harminka — Fri, 07 Aug 2009 07:48:10 -0500

New work by MIT cancer biologists shows that the interplay between two key genes that are often defective in tumors determines how cancer cells respond to chemotherapy.

Drug combination may be effective against deadly melanoma

harminka — Fri, 06 Mar 2009 10:06:56 -0600

By targeting and disabling a protein frequently found in melanoma tumors, doctors may be able to make the cancer more vulnerable to chemotherapy, according to early results of a clinical study conducted by researchers in the Duke Comprehensive Cancer Center.

New technique helps to predict breast cancer chemotherapy outcome

harminka — Mon, 02 Feb 2009 10:43:40 -0600

Chemotherapy is an integral part of modern cancer treatment, but it's not always effective. Successful chemotherapy depends on the ability of anticancer drugs to escape from the bloodstream through the leaky blood vessels that often surround tumors.

Scattered light rapidly detects tumor response to chemotherapy

harminka — Mon, 02 Feb 2009 10:33:44 -0600

New technology developed by Duke University bioengineers can help clinicians more precisely detect whether specific cancer drugs are working, and should give basic researchers a powerful new tool to better understand the underlying mechanisms of cancer development.

Role of circadian clock in response to chemotherapy

harminka — Tue, 13 Jan 2009 10:38:34 -0600

For years, research has hinted that the time of day that cancer patients receive chemotherapy can impact their chances of survival. But the lack of a clear scientific explanation for this finding has kept clinicians from considering timing as a factor in treatment.

MIT creates tiny backpacks for cells

harminka — Thu, 06 Nov 2008 08:11:26 -0600

MIT engineers have outfitted cells with tiny "backpacks" that could allow them to deliver chemotherapy agents, diagnose tumors or become building blocks for tissue engineering.

Healthy eating can improve cancer patients' response to chemotherapy

harminka — Thu, 23 Oct 2008 00:36:33 -0500

The leading cause of death in all cancer patients continues to be the resistance of tumor cells to chemotherapy, a form of treatment in which chemicals are used to kill cells.

Bisphenol A linked to chemotherapy resistance

harminka — Thu, 09 Oct 2008 08:00:44 -0500

Exposure to bisphenol A (BPA) may reduce the effectiveness of chemotherapy treatments, say University of Cincinnati (UC) scientists.

Advance on new generations of chemotherapy and antiviral drugs

harminka — Mon, 08 Sep 2008 08:47:23 -0500

Researchers are describing progress toward developing a new generation of chemotherapy agents that target and block uncontrolled DNA replication — a hallmark of cancer, viral infections, and other diseases — more effectively than current drugs in ways that may produce fewer side effects.

How chemo kills tumors

harminka — Thu, 07 Aug 2008 11:16:34 -0500

Dr Stephen Taylor and Karen Gascoigne at the University’s Faculty of Life Sciences have taken a new systematic approach to studying anti-mitotic drugs, which are used extensively for breast or ovarian cancer in the UK.