cell death

Nerve Signals Contribute to Motor Neuron Death in Amyotropic Lateral Sclerosis

harminka — Thu, 22 Jan 2009 02:56:10 -0600

A group led by Dr. Lee Martin of Johns Hopkins University School of Medicine discovered that loss of inhibitory neuron signaling may lead to motor neuron cell death in ALS. They present their data in the February 2009 issue of The American Journal of Pathology.

Protein that amplifies cell death discovered

harminka — Thu, 15 Jan 2009 02:14:32 -0600

Scientists at Albert Einstein College of Medicine of Yeshiva University have identified a small intracellular protein that helps cells commit suicide.

On Switch for Cell Death Signaling Mechanism

harminka — Tue, 06 Jan 2009 07:11:55 -0600

Scientists at Burnham Institute for Medical Research (Burnham) have determined the structure of the interactions between proteins that form the heart of the death inducing signaling complex (DISC), which is responsible for triggering apoptosis (programmed cell death).

Genes that control cell death fingered in age-related hearing loss

harminka — Fri, 17 Oct 2008 08:01:40 -0500

Several genes that play a role in how our body's cells normally auto-destruct may play a role in age-related hearing loss, according to research published online in the journal Apoptosis – a journal devoted to the topic of cell suicide, or programmed cell death.

1 dose of EPO may halt cell suicide following heart attack

harminka — Thu, 09 Oct 2008 08:02:35 -0500

Molecular imaging agent reveals beneficial effects of tissue-protecting hormone, according to article in The Journal of Nuclear Medicine

How choline compounds change when apoptosis occurs?

harminka — Wed, 24 Sep 2008 07:10:51 -0500

Apoptosis is a programmed, active, highly selective mechanism of cell death. Abnormal regulation of apoptosis can lead to disorders such as cancer. The field of apoptosis research has undergone an explosion of new knowledge over the past decade.

Novel structure proteins could play a role in apoptosis

harminka — Fri, 25 Jul 2008 01:44:14 -0500

Isoforms from Novel Structure Proteins (NSP), a new family of genes discovered by researchers in the Sbarro Institute for Cancer Research and Molecular Medicine in Temple University's College of Science and Technology, could be involved in apoptosis or programmed cell death.

Key step in mechanism of cell death revealed

harminka — Mon, 12 May 2008 08:38:44 -0500

A team of medical researchers led by Dr Ruth Kluck at Melbourne’s Walter and Eliza Hall Institute (WEHI) has discovered a key step in the mechanism by which cells destroy themselves. In this process, called “apoptosis”, certain proteins cause the cell to self-destruct by puncturing its “power plant.” How the proteins do this has been clarified by the WEHI team. The discovery is an important step towards the identification of targets for drugs designed to regulate cell death.

St. Jude researchers find key step in programmed cell death

harminka — Sat, 01 Mar 2008 04:04:10 -0600

Investigators at St. Jude Children’s Research Hospital have discovered a dance of proteins that protects certain cells from undergoing apoptosis, also known as programmed cell death. Understanding the fine points of apoptosis is important to researchers seeking ways to control this process.

New drug targets for preventing cell death

harminka — Thu, 28 Feb 2008 12:52:03 -0600

A new compound that blocks an early step in cell death could lead to a novel class of drugs for treating heart attacks and stroke.

Overexcited neurons not good for cell health

harminka — Tue, 18 Dec 2007 00:00:30 -0600

Neurotransmitters have consequences. They initiate events that are critical to a healthy life, giving us the ability to move, to talk, to breathe, to think. But that’s if the neurotransmitters are getting it right and sending proper signals downstream to muscle cells, neurons or other cells.

Identification of new genes shows complex path to cell death

harminka — Sat, 15 Dec 2007 02:36:36 -0600

Can a tiny winged insect’s salivary glands really tell us about processes relevant to human disease" Yes, according to a new study by researchers at the University of Massachusetts Medical School (UMMS), who gained new insights into autophagy—a cellular degradation process associated with a form of programmed cell death—by studying the salivary gland cells of the fruit fly.