tumor suppressor genes

Regulatory molecule for tumor formation or suppression identified

harminka — Tue, 17 Mar 2009 14:51:51 -0500

One of the small regulatory molecules, named microRNA-125b, is a novel regulator of p53, an important protein that safeguards cells against cancers, Singapore and U.S. scientists report in the March 17, 2009 issue of the journal Genes & Development.

Experimental therapy turns on tumor suppressor gene in cancer cells

harminka — Tue, 20 Jan 2009 12:06:28 -0600

Researchers at Mayo Clinic have found that the experimental drug they are testing to treat a deadly form of thyroid cancer turns on a powerful tumor suppressor capable of halting cell growth. Few other cancer drugs have this property, they say.

Tumor suppressor that manages cellular cleaning, recycling proceses

harminka — Fri, 04 Jul 2008 00:46:27 -0500

Researchers at the University of Southern California (USC) have identified a specific tumor suppressor that manages membrane traffic routes for cellular cleaning and recycling.

Study details regulation of vital tumor suppressor gene p53

harminka — Thu, 06 Sep 2007 11:09:18 -0500

So vital is the p53 tumor suppressor gene in controlling cancer that its dysfunction is linked to more than half of human cancers. At the same time, the gene’s capacity for shutting down cell growth, even causing cells to commit suicide if necessary, is so absolute that it must be tightly regulated to maintain the optimal balance between protecting against cancer and permitting normal growth.

Loss is linked to common lung cancer

harminka — Sat, 25 Aug 2007 01:17:25 -0500

Little-known bits of RNA help master tumor suppressor gene do its job, U-M cancer researchers find

Pathway links inflammation, angiogenesis, breast cancer

harminka — Thu, 09 Aug 2007 13:00:05 -0500

A well-known inflammatory protein spawns an enzyme that inactivates two tumor-suppressing genes, ultimately triggering production of new blood vessels to nourish breast cancer cells, researchers at The University of Texas M. D. Anderson Cancer Center report in the August edition of the journal Cell.

New gene that prevents multiple types of cancer

harminka — Sat, 10 Feb 2007 01:41:26 -0600

Role of Rb in mammalian stem cells

harminka — Mon, 01 Jan 2007 02:59:38 -0600