tumor growth

Key to aggressive breast cancer

harminka — Fri, 31 Oct 2008 09:01:09 -0500

In trying to find out why HER2-positive breast cancer can be more aggressive than other forms of the disease, UC Davis Cancer Center researchers have surprisingly discovered that HER2 itself is the culprit. By shutting down its own regulator gene, HER2 creates a permissive environment for tumor growth.

Receptor could halt blinding diseases, stop tumor growth, preserve neurons after trauma

harminka — Tue, 07 Oct 2008 02:37:06 -0500

An international team of researchers has discovered what promises to be the on-off switch behind several major diseases.

Vitamin C injections slow tumor growth in mice

harminka — Tue, 05 Aug 2008 11:52:23 -0500

High-dose injections of vitamin C, also known as ascorbate or ascorbic acid, reduced tumor weight and growth rate by about 50 percent in mouse models of brain, ovarian, and pancreatic cancers, researchers from the National Institutes of Health (NIH) report in the August 5, 2008, issue of the Proceedings of the National Academy of Sciences.

Blue light used to harden tooth fillings stunts tumor growth

harminka — Wed, 25 Jun 2008 07:20:29 -0500

A blue curing light used to harden dental fillings also may stunt tumor growth, Medical College of Georgia researchers say.

Retraining immune cells to kill tumors

harminka — Mon, 19 May 2008 13:04:08 -0500

Immune cells called macrophages can destroy tumor cells by producing inflammatory proteins that are toxic to the tumor. But the environment inside the tumor somehow halts this production and instead causes the cells to make proteins that promote tumor growth.

Human vascular system in mice

harminka — Mon, 14 Apr 2008 13:29:28 -0500

The formation of new blood vessels, or angiogenesis, is an Achilles’ heel of tumor growth, because tumors depend on the supply of oxygen and nutrients for survival. Therefore, for some years now substances called angiogenesis inhibitors have been used in cancer treatment to suppress this process.

Blood pressure enzyme can have tumor-sensing role

harminka — Tue, 08 Apr 2008 10:08:19 -0500

By increasing production of a blood pressure-regulating enzyme in mice, researchers have found they can enhance the mouse immune system's ability to sense tumor growth.

New target for cancer therapy may improve treatment for solid tumors

harminka — Mon, 03 Mar 2008 13:25:13 -0600

Targeting and killing the non-malignant cells that surround and support a cancer can stop tumor growth in mice, reports a research team based at the University of Chicago Medical Center in the March 1, 2008, issue of the journal Cancer Research. The discovery offers a new approach to treating cancers that are resistant to standard therapy.

Innocent bystanders can be cause of tumor development

harminka — Mon, 03 Mar 2008 12:15:49 -0600

Tumor growth has commonly been viewed as a result of mutations in a given cell that will therefore proliferate uncontrollably. However, a study conducted at the University of Helsinki, Finland, has demonstrated that in certain type of gastrointestinal polyps, the cause of tumor development are mutations in the smooth muscle cells, previously regarded as “innocent bystanders”.

Gene dose affects tumor growth

harminka — Fri, 04 Jan 2008 02:04:51 -0600

Researchers at Johns Hopkins and Ohio State University have found that the number of copies of a particular gene can affect the severity of colon cancer in a mouse model. Publishing in the Jan. 3 issue of Nature, the research team describes how trisomy 21, or Down syndrome in humans, can repress tumor growth.

Hormone links sleep, hunger and metabolism

harminka — Thu, 15 Nov 2007 10:08:36 -0600

While investigating how the hormone orexin might control sleep and hunger, researchers at UT Southwestern Medical Center have discovered, to their surprise, that it activates a protein, HIF-1, long known to stimulate cancerous tumor growth.

Zinc transporters regulate pancreatic cancer

harminka — Tue, 13 Nov 2007 10:11:21 -0600

Zinc, an important trace element for healthy growth and development, can be related to pancreatic cancer.