cancer development

Protein switch suppresses skin cancer development

harminka — Tue, 09 Sep 2008 09:41:47 -0500

The protein IKKalpha (IKKα) regulates the cell cycle of keratinocytes and plays a key role in keeping these specialized skin cells from becoming malignant, researchers at The University of Texas M. D. Anderson Cancer Center report in the Sept. 9 issue of Cancer Cell.

MIT confirms link between inflammation, cancer

harminka — Tue, 03 Jun 2008 02:01:20 -0500

Chronic inflammation of the intestine or stomach can damage DNA, increasing the risk of cancer, MIT scientists have confirmed.

Cumulative radiation exposure shows increased cancer risk

harminka — Thu, 29 May 2008 07:25:20 -0500

According to a new study, patients are receiving estimated doses of radiation from medical diagnostic imaging studies, such as CT (or “CAT”) scans, that may be detrimental to their long term health, putting them at an increased risk of developing cancer. To date, emergency physicians have not been made aware of the cumulative amount of radiation that their patients receive.

Novel enzyme inhibitor paves way for new cancer drug

harminka — Fri, 16 May 2008 06:00:26 -0500

Combining natural organic atoms with metal complexes, scientists at The Wistar Institute have developed a new type of enzyme inhibitor capable of blocking a biochemical pathway that plays a key role in cancer development.

Key gene involvement in cancer development

harminka — Wed, 16 Apr 2008 14:06:05 -0500

Oregon Health & Science University researchers have identified a gene that is necessary in eliminating cancer cells.

Mesothelioma model reproduces human disease

harminka — Tue, 11 Mar 2008 01:12:57 -0500

Scientists have established a mouse model for human malignant mesothelioma (MM) that will provide valuable insight into cancer development and progression along with new directions for design of therapeutic strategies.

A taxing issue: How human T-lymphotropic virus

harminka — Thu, 31 Jan 2008 12:31:32 -0600

Researchers have identified a potential new mechanism through which human T-lymphotropic virus type-1 (HTLV-1) causes leukemia in adults. The findings, published this week in the online open access journal Retrovirology, represent the first time that a reduction in histone protein levels has been linked to viral infection and the development of cancer.

Hopkins researchers paint picture of cancer-promoting culprit

harminka — Sat, 05 Jan 2008 02:16:50 -0600

They say that a picture can be worth a thousand words. This especially is true for describing the structures of molecules that function to promote cancer.

Keeping at-risk cells from developing cancer

harminka — Mon, 10 Dec 2007 23:53:26 -0600

Researchers at Johns Hopkins have discovered that cancers arising from epigenetic changes - in this case the inappropriate activation of a normally silent gene - develop by becoming addicted to certain growth factors.

Overweight, obesity cause 6,000 cancers year in UK women

harminka — Wed, 07 Nov 2007 06:56:16 -0600

The study shows that overweight and obese women in the UK are at a higher risk of developing and dying from cancer. In fact, the researchers estimate that 5% of all cancers (about 6,000 annually) are attributable to being overweight or obese.

Controlling for size may also prevent cancer

harminka — Fri, 21 Sep 2007 05:29:50 -0500

Scientists at Johns Hopkins recently discovered that a chemical chain reaction that controls organ size in animals ranging from insects to humans could mean the difference between normal growth and cancer.

No link between working night shift and increased risk of cancer

harminka — Thu, 23 Aug 2007 00:26:26 -0500

Working the night shift doesn't appear to increase the risk of developing cancer, suggests the findings of a new study of Swedish workers.